An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells
نویسندگان
چکیده
منابع مشابه
An overlapping protein-coding region in influenza A virus segment 3 modulates the host response.
Influenza A virus (IAV) infection leads to variable and imperfectly understood pathogenicity. We report that segment 3 of the virus contains a second open reading frame ("X-ORF"), accessed via ribosomal frameshifting. The frameshift product, termed PA-X, comprises the endonuclease domain of the viral PA protein with a C-terminal domain encoded by the X-ORF and functions to repress cellular gene...
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ژورنال
عنوان ژورنال: Nature Microbiology
سال: 2018
ISSN: 2058-5276
DOI: 10.1038/s41564-018-0297-1